International Journal of Medical and Health Research

ISSN: 2454-9142

Vol. 6, Issue 4 (2020)

Assessment of serum magnesium level and its correlation with febrile convulsion in children of north Bihar Region

Author(s): Dr. Kripa Nath Mishra, Dr. Pankaj Kumar, Dr. Anil Kumar
Abstract: Background: Febrile seizure is defined as seizure that occurs between the age of six month to five year, with temperature of more than 38ºC (100.4ºF) or higher, that are not the result of CNS infection or any metabolic imbalance, and that occur in the absence of a history of prior afebrile seizures. Low level of magnesium in serum below baseline is characterized by hyper-excitability of central nervous system leading to convulsions. Alteration in blood level of sodium, potassium, calcium, and magnesium has been implicated in the pathogenesis of developing seizures. Normal level of this electrolyte is necessary for CNS function. Magnesium is essential for membrane stabilization and nerve conduction. Hypomagnesaemia is characterized by hyper-excitability of CNS leading to convulsions. Aim: Assessment of serum magnesium level and its correlation with febrile convulsion in admitted children of hospital. Materials and Methods: This study was conducted in Department of pediatrics, Darbhanga Medical College & hospital, Laheriasarai, Darbhanga, Bihar from November 2018 to October 2019. This study was Observational prospective study and total 130 children of febrile convulsion was selected. Results: Out of 130 total cases, 113 (8 6. 6 7%) were typical febrile convulsions and 17 (1 3. 3 3 %) were atypical febrile convulsions. Hypomagnesaemia was seen in 21 (1 6 %) children, out of these 1 0 (4 7. 3 6%) cases were males and 11 (52.64%) cases were females. Out of 17 atypical febrile convulsions, only 2 cases were having hypomagnesaemia and 15 were having normal magnesium level. Conclusions: From this study we conclude that there was some association between hypomagnesaemia and typical febrile convulsions. We got positive correlation between level of serum magnesium and febrile convulsions. However large clinical studies are required to establish the associations of hypomagnesaemia and febrile convulsions
Pages: 39-42  |  53 Views  13 Downloads
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