Palatogingival groove is a developmental anomaly that often causes severe periodontal defects and often appear on maxillary lateral and central incisors. Various techniques have been adopted to eliminate the groove and regenerate lost periodontium. Careful endodontic and periodontal procedures may restore the form and function. This report presents a case of a maxillary lateral incisor with a deep palatogingival groove extending up to the root apex with severe periodontal destruction. In the present case; root canal therapy, and sealing of the groove with Biodentine was done followed by placement of platelet‑rich fibrin (PRF) membrane.1 year follow up radiograph revealed reduction of radiolucency around 12 and the treatment outcome was gain in attachment, reduction in pocket depth, and deposition of bone in the osseous defect. A 12 month follow‑up is included.