Impact of visual correction in people suffering with oculo-cutaneous Albinism in central region of Uttar Pradesh
Subodh Kumar Agarwal MS, Virendra Kumar Pal MS, YS Sirohi MS, Rahul Bhardwaj MS, Sandeep Sharma MS
Introduction: Albinism comes from the Latin albus, which meaning white, and is a group of Hereditary disorders in which the Biosynthesis of the Pigment Melanin is absent or reduced. Oculo-cutaneous Albinism (OCA) is a Heterogeneous and Autosomal recessive disorder that involves a lack of Pigment in the Skin, Hair, and Eyes, and is accompanied by Optic defects such as Photophobia, Strabismus, Poor vision, and Nystagmus. Materials and Methods: This was a prospective community-based Study conducted at tertiary care Hospital in central region of Uttar Pradesh during 1 August 2016 to June 2020. The Department of Ophthalmology collected 100 People accepting enrolment voluntarily suffering with Albinism. The diagnostic criteria for OCA were: presence any two criteria as 1-Presence of Iris Transillumination 3-Depigmentation of the Skin 3-Retinal hypopigmentation 4- Depigmentation of the Hairs and Nails. Results: 100 Patients with OCA were included, mean age 20 years with 60 (60%) males and 40 females (40%). The largest proportions of Participants (40%) were between16 to 25yrs. based on World Health Organization Classification for Visual impairment (VI) all Patients were categorized into Normal-Mild, Moderate Visual Impairment, Severe Visual Impairment, Blindness respectively. Conclusion: There is high prevalence of Refractive, non-Refractive and mixed ophthalmic disorders among Albinos There was significant improvement in Visual Acuity and function following Optical correction and alignment in people with Albinism, despite overall subnormal Acuity. Refractive correction should be encouraged for People with Albinism.