International Journal of Medical and Health Research

International Journal of Medical and Health Research


International Journal of Medical and Health Research
International Journal of Medical and Health Research
Vol. 6, Issue 8 (2020)

Cell mediated immunity as a weapon to fight against COVID19-A brief review


S Kalpana, Raghul Ramachandran

COVID-19 is not the first severe respiratory disease outbreak caused by the coronavirus. Just in the past two decades, coronaviruses have caused three epidemic diseases, namely, COVID-19, severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS). At present, the cases of COVID-19 have been found in many countries around the world. Here, we provide an outline of the pathophysiology of SARS-CoV-2 infection. Also, we describe the interaction of SARS-CoV-2 with the cell mediated immune system and the subsequent contribution of dysfunctional immune responses to disease progression. Understanding the immunological response to the SARS-CoV-2 viral infection will help us to develop successful treatments and vaccines, identify vulnerable groups and help inform public health measures to control the coronavirus outbreak.
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