Study of comparison of Procalcitonin and C-reactive protein concentration as early marker of neonatal sepsis

Dr. Saroj Kumar; Dr. Pradeep Kumar

Study of comparison of Procalcitonin and C-reactive protein concentration as early marker of neonatal sepsis

Authors
Dr. Saroj Kumar, Dr. Pradeep Kumar

Abstract
Objectives: To compare between C-reactive protein (CRP) and Procalcitonin (PCT) regarding diagnosis and outcome of neonatal sepsis.

Participants: Seventy newborn Infants admitted to NICU for sepsis management.

Results: Of the total 70 Neonates admitted in NICU, 31.4%, 42.9% and 25.7% were categorized as proven sepsis, suspected sepsis and clinical sepsis respectively. Procalcitonin was positive in 100% compared to the CRP positivity in 63.6% of the proven sepsis cases. Mortality rate is significantly increased in proven sepsis compared to clinical sepsis.

Intervention: Sepsis workup laboratory tests. Main Outcome Measures: Specific diagnostic and prognostic impact of the tests.

Conclusion: Comparing with CRP, PCT is not only a good diagnostic measure of neonatal sepsis but also effective predictor of sepsis outcome.

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