A histopathological study of lesions of nasal cavity and para nasal sinuses
Charu Chandra, *2 Pragat Gupta
Background: Lesions of nasal cavity are quite common. It can be neoplastic and non-neoplastic. Diseases of the nasal cavity include viral, bacterial and fungal infections, nasal cavity tumors as well as inflammations of the nasal mucosa. the present study was carried out to record the various neoplastic and non-neoplastic lesions of nasal cavity and paranasal sinuses. Materials & Methods: The present study was conducted in the department of general pathology in year 2015. It comprised of 108 cases reported to the department. Information such as name, age, gender, chief complaint, clinical and radio graphical findings etc. were retrieved from OPD record. All the biopsies were fixed with 10% buffered formalin. Hematoxilin and eosin staining was done. Results: Out of 108 lesions, 52 were non neoplastic and 56 were neoplastic lesion. The difference was non -significant (P- 1). 42 lesions were inflammatory polyp, 8 were fungal infection, 1 case each was of nasal glioma and rhiniosporidiosis. The difference was significant (P < 0.05). 30 lesions were benign and 26 were malignant. The difference was significant (P< 0.05). Figuer III shows that benign neoplastic lesions were inverted papilloma (14), schwannoma (6), angiofibroma (8) and capillary hemangioma (2). The difference was significant (P< 0.05). Malignant neoplastic lesions were squamous cell carcinoma (14), basal cell carcinoma (2), neuroblastoma (1), round cell tumor (3), PNT (1), plasmacytoma (4) and hemangiopericytoma (1). The difference was significant (P< 0.05). Conclusion: Lesions of nasal cavity and paranasal sinuses are of paramaount importance because of high mortality and morbidity. Histopathology is the key to differentiate one lesion from another which is beneficial for the management of lesion.