International Journal of Medical and Health Research

a. To assess the effect of pregnancy on leiomyomas.

b. Effect of leiomyomas on pregnancy

c. The maternal morbidity and mortality and

d. The perinatal outcome in pregnancies associated with leiomyoma.

Materials and Methods: This clinical study was conducted at Department of Obstetrics and Gynecology, MGM Medical College, Jamshedpur from July 2015 to June 2017 on 80 pregnant women diagnosed with uterine leiomyoma.

Results: Out of these 40 cases, 87.5% were more then 25 years old. Diagnosis was done by Antenatal ultrasound in 87.5% of cases. In 60 percent of cases, leiomyoma was subserous in location. In 50 percent of cases the size of Leionyma ranged from 10-50 cc in size. In 77.5% the leiomyma was single, but in 15 % of cases their number was three or more.

During the Period of Pregnancy the size of the leiomyoma: Remained unaltered in 87.5% cases, increased in size in 20% and decreased in size in 10% of cases 35% of cases developed complications out of which 12.5% percent has complete abortions.5.5% has placental abruption, 5.7% had premature rupture of membrane and 8.6% preterm labour.

22.5% of patients delivered vaginally whereas 65% if patient underwent lower segment caesarean section.

Indications for caesarean section were varied but major (26.9%) indication was malpresntation, 11.5% for myoma >30cc & 7.7% for leiomyoma in lower uterine segment.

Caesarean myomectomy was possible in 50% of patients: APGAR Score - 5.7% of newborns had an APGAR Score <7at 1 min, all had an AGAR Score >7at 5 mins. 22.9% of babies were lowbirth weight babies.

Conclusion: It is difficult to predict the course of leiomyoma in pregnancy. Once diagnosed regular & repeated followup examination helps in avoiding the complications and achieving good pregnancy outcome.