Nutritional depletion is a prevalent finding in patients who have COPD. Several studies have demonstrated that under nutrition is an independent predictor of all cause and respiratory morbidity and mortality in COPD and has an additive effect with other factors that increase mortality. Investigators have identified a positive correlation between body weight and the Forced Expiratory Volume in the 1st second. Even among stable COPD patients there is a high proportion of under nutrition. COPD patients are at risk of weight loss and nutritional deficiencies because of a 15 to 25% increase in resting energy expenditure from breathing; a higher energy cost of daily activities; reduced caloric intake 2 relative to need because of dyspnea; and the catabolic effect of inflammatory cytokines such as TNF-α5. Hence based on above reported findings the present study was planned to estimate the nutritional status of stable COPD patients The present study was planned in Narayan Medical College and Hospital, Jamuhar Sasaram, Bihar, India. Total 100 cases of the COPD were enrolled in the present study. All patients were classified based on combined COPD assessment by revised Global Initiative for Chronic Obstructive Lung Disease GOLD 2011. The study group was consist of male and female patients age more than 40 years and less than 80 years, diagnosed to have COPD by spirometry. The body mass index (BMI) was calculated as weight (in Kg)/height2 (in metres). Mid-arm circumference (MAC) measurement was done in the non-dominant arm of the patient using a flexible measuring tape. Blood samples were analyzed for albumin, total protein, blood urea, serum creatinine. Normal ranges of our biochemistry laboratory are as follows: Albumin: 3.5-5.3g/l, total protein: 6.0-8.3g/l, blood urea: 7- 35 mg/dl and creatinine: 0.6-1.2 mg/dl. From the above observations, we may conclude that patients with COPD are generally malnourished and the prevalence is more in a developing country like India. Nutritional interventions in the form of dietary supplement have shown improvement in anthropometry, exercise capacity and HRQL but did not show any significant improvement in pulmonary function.