Anaemia is a condition that causes a low red blood cell count and insufficient levels of hemoglobin, a protein that carries oxygen. Anaemia can cause symptoms that might add to the weakness and tiredness that people with rheumatoid arthritis sometimes experience. However, treatments are available to help reduce the symptoms of anaemia. According to some estimates, 30–70 percent of people with rheumatoid arthritis develop anaemia. The study was planned in Narayan medical College and Hospital in Department of Medicine. The total 50 patient were selected and enrolled into the study. The 25 patients were identified with the RA condition and 25 patients were enrolled as normal patients. The different serum parameters like Haemoglobin, Serum iron, Serum Total iron binding capacity and Serum Ferritin were monitored in both study group patients. There is no known prevention for rheumatoid arthritis (RA) other than the reduction of contributory factors. Therapy goals are to reduce pain and inflammation and improve quality of life. Surgery to repair, replace or fuse joints may help in serious conditions.