Adherence to guidelines for amiodarone monitoring at Benghazi cardiac center, Benghazi, Libya
Alia Buzeid, Adela H Elamami
Background: Amiodarone is anti-arrhythmic but the clinical usefulness is complicated by its extensive side effect which necessitates careful patient’s selection and monitoring.Objective: The purpose of this study is to assess adherence to published guidelines for monitoring amiodarone at out patients setting of Benghazi cardiac center. Patients & Method: Across sectional retrospective study of out patients attending Benghazi cardiac center from April 2009 to April 2010 who were chronically on amiodarone therapy assessed retrospectively regarding their demographic data, reason for initiation, duration of therapy, the occurrence and timing of laboratory tests which recommended by guidelines. Thyroid function test was sent during the study for all patients. Results: 22 out of 43 patients on amiodarone who attend the center in the study time frame was interviewed in OPD and their files were searched .14 were female, the mean age was 59.8+/-10.3, mostly the indication for amiodarone therapy was ventricular arrhythmia 17/22 (77.3%), a trial 4/22(18.2%), and no clear indication in 4.5%. Mean duration of therapy was 14.7+/- 10.5 months, range (6-36), regarding baseline monitoring the adherence rate for TFT, LFT, CXR and PFT were 27.3%, 4.5%, 0%, 0%, while chronic monitoring 4.5%, 4.5%, 0% respectively. TFT during the study shows that the thyroid dysfunction rate was 42.11%. Conclusion: The adherence rate to published monitoring guidelines and Package insert recommendations for amiodarone in our Benghazi cardiac center was low.
Alia Buzeid, Adela H Elamami. Adherence to guidelines for amiodarone monitoring at Benghazi cardiac center, Benghazi, Libya. International Journal of Medical and Health Research, Volume 2, Issue 12, 2016, Pages 32-35