Paracetamol (acetaminophen, PCM) is widely used as an over-the-counter analgesic and antipyretic drug. It’s a remarkably safe drug devoid of serious side effects in therapeutic doses. Intake of large doses of PCM may result in severe hepatic necrosis. While hepatoxicity is its well-known side effect, paracetamol is very rarely implicated to be a culprit of Steven- Johnson syndrome.
NS Neki, Gagandeep Singh Shergill, Amritpal Singh, Amanpreet Kaur, Puneet Bans Sidhu, Taranjit Singh. Paracetamol induced Steven- Johnson syndrome-toxic epidermal necrolysis overlap: The unusual suspect. International Journal of Medical and Health Research, Volume 2, Issue 12, 2016, Pages 59-61