International Journal of Medical and Health Research

Authors
S Karikalan, Dr. A Mohankumar

Abstract
Streptococcus mutans was a leading causative agent for tooth decay or dental caries around the world wide. Dental caries and endocarditis diseases are leading to cause more critical stage in human beings and it was created by S. mutans. All the samples were collected around dental clinics and hospitals of Tirupur, Tamilnadu from the period of 2013 to 2015. Selective isolates of S. mutans were identified by phenotypic and Biochemical characterization. Only 10 isolates were selected for antibiotic susceptibility test. 6 antibiotics were completely resistant to tested isolates among them 4 antibiotics showed 100% resistant. This present investigation was conducted for screening the best antimicrobial drugs against S. mutans. But, this study showed multi drug resistant species were identified from the tested isolates of S. mutans against 14 commercial drugs. These are used against dental caries patients and were practiced in dental clinics and hospitals. Hence, need new powerful drugs against dental caries commonly in clinical trials.