Methods: A total of 106 clinical isolates were collected and processed and identified by standard microbiological method and biochemical tests and antimicrobial susceptibility testing was carried out by a standard disc diffusion method.

Result: Out of all clinical isolates 83.49% of these isolates were Salmonella typhi and 16.50% were Salmonella paratyphi A. Salmonella typhi was found to be most sensitive to levofloxacin, aztreonam, imipenam and less sensitive to ciprofloxacin (25.58%), azithromycin (27.9%), amoxyclav (37.2%). Salmonella paratyphi A was found to be most sensitive to ceftriaxone, levofloxacin, aztreonam, cefixime, gatifloxacin, imipenam and showed least sensitive to azithromycin (23.53%), ciprofloxacin (29.41%). Overall 44.7% (n= 46) of the isolates were multidrug-resistant.

Conclusion: This study suggests the further monitoring of efficacy of older and newer antimicrobial agents for the proper treatment and management of enteric fever.