In its daily practice, the dental surgeon uses materials intended for short time, ensuring a transition towards proper treatments. In endodontics, several biomaterials are likely to be used in the treatment of pulp periapical diseases. The diversity of biomaterials obliges the practitioner to analyze all criteria of selection before establishing the indication of the biomaterial to use. This study aims to analyze the endodontic medication in clinical practice. It was a descriptive and cross-sectional study regarding dental surgeons practicing in Dakar. A little less than ¾ of dental surgeons (74.5%) perform one to four endodontic treatments daily. To justify their choice, 196 dental surgeons used these biomaterials because of their success in treatment. However, it is recommended that they receive continuous training in dentistry to update their knowledge and practice to provide patients with better care.