International Journal of Medical and Health Research

Authors
B Shivaranjani, Dr. T Sanjay, G Praneeth, *P Kishore

Abstract
Traumatic brain injury (TBI) is a major health condition where the therapy and the outcome are based on the clinical presentation, severity of injury and secondary brain insults. The present study aimed to assess the outcome of the patients with TBI. It is an observational study conducted in 200 patients during the six months study period. Various parameters are considered to correlate the outcome. 79.5% patients had favorable outcomes and 14.5% patients had severe disability. Overall mortality rate was found to be 5%. Odds ratio has shown positive association for age and outcome. Mortality was seen high in patients with Glasgow Coma Scale 3-8. Electrolyte derangements associated with hyperosmolar therapy found to be statistically significant (P =0.0001) in affecting the outcome as hypernatremia was seen in majority of the patients with GOS grade 1. Age and therapy provided are the significant factors affecting the outcome of TBI. Initial GCS has significantly predicted the outcome of the patients. As the hyperosmolar therapy is the main stay in reduction of ICP in TBI patients, 24 hour monitoring should be done to prevent the electrolyte derangements which are found to significantly affect the outcome of the TBI patients.