Sickle cell anaemia is a multisystem disease associated with end-organ damage, which can adversely affect the growth anddevelopment of children. There is no enough data on the effect of this disease on the growth and development of children. The study was conducted in 25 Sickle cell diseases & 25 normal childrens. Both sickle cell disease male and female children were shown tohavestatistically significant lower weights, heights, sitting heights, interacromial diameter and intercristal diameter ascompared to normal children. The further investigations are needed in this study for growth and its quantitative relation with the proteins, caloric intake and haematological index of the children.Sickle cell anaemia is not causing significant adverse effect on the growth of children; but it has a transient negative effect onthe growth of primary school going children.