Background: Hypertensive disorders are among the commonest medical disorders during pregnancy & continue to be a major cause of maternal, perinatal morbidity and mortality worldwide. In developing countries like India, incidence is 3-14%. Objective: In the present study we observe the status of lipid-peroxidation, lipid-profile & β-hCG levels in pre-eclampsia. The present study shows the increased lipid-peroxidation, lipid-profile except serum HDL and decreased β-hCG levels. Methods: The present study is carried out on in the Department of Biochemistry and Department of Obs and Gynae on 200 antenatal patients attending outpatients in S.R.N Medical College Allahabad, over a period of twelve month during 2010-2012. Result: In the present study we found increased lipid-profile (except HDL) and β- hCG levels in preeclampsia as compared to control. These results are statistically significant. Conclusion: It is evident from the study that antenatal patients with elevated levels of serum βhCG and deranged lipid profile are at increased risk of developing hypertensive disorders of pregnancy in advanced pregnancy.