We have treated 4037 patients with various forms of cholelithiasis. Mirizzi syndrome was diagnosed in 56 patients, accounting for 1.38%. Patients with Mirizzi’s syndrome were divided into 2 groups. The control group includes 19 patients after of laparotomy cholecystectomy. The main group consists of 37 patients after cholecystectomy through the minimally invasive approach. Evaluation of ultrasound results before the surgery, allowed diagnosing Mirizzi’s syndrome in 37 (67.4%) patients. Assessment of the echogram showed signs that allowed us to suspect Mirizzi’s syndrome before the surgery. In assessment of the ERCP results the pathognomonic signs for Mirizzi’s syndrome were considered typical compression of the common bile duct from outside, or the presence of cholecystcholedochal fistula that was found in 32 (58.3%) patients.