International Journal of Medical and Health Research

International Journal of Medical and Health Research


International Journal of Medical and Health Research
International Journal of Medical and Health Research
Vol. 3, Issue 9 (2017)

Study of effect of aspirin on suxamethonium induced myalgia


Dr. Shakir Najfi

The present study was planned to know the outcome of oral aspirin in dropping the incidence of post-operative myalgia triggered by administration of suxamethonium and to relate it with precurarization (with pancuronium) and with a control. GROUP A: Patients in this group were precurarised by giving injection pancuronium 0.01 mg/kg body weight intravenously three minutes before commencement of induction of anesthesia. GROUP B: Patients in this group were given soluble aspirin (tablet Disprin) 600 mg orally one hour before induction of the anesthesia. GROUP C: No pretreatment was given In group A there are 4 cases are of mild pain and 1 cases of moderate pain. In group B there are 5 cases are of mild pain and 2 moderate pain. In group C there are 8 cases are of mild pain and 6 moderate pain. In Group A patients without aspirin 15 cases showed no fasciculation and 5 cases showed mild fasciculation. In group B administered with the aspirin 2 cases of no fasciculation observed, 12 cases are of mild fasciculation, 4 cases are of moderate fasciculation and 2 cases are of severe fasciculation. Preoperative aspirin 600mg orally 1 hr before operation effectively reduces Suxamethonium induced pain and avoid complications associated with pretreatment with non-depolarising agents.
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How to cite this article:
Dr. Shakir Najfi. Study of effect of aspirin on suxamethonium induced myalgia. International Journal of Medical and Health Research, Volume 3, Issue 9, 2017, Pages 159-161
International Journal of Medical and Health Research