Background: European Association has considered percutaneous nephrolithotomy (PCNL) as first option for large, multiple or inferior calyx stones. Open surgery has been replaced by PCNL because of its cost effectiveness, lower morbidity, shorter operative time and lower postoperative complications.

Aims and Objectives: To study the post PCNL complications among the patients with renal stone.

Materials and Methods: A total ninety patients with renal stone were studied at SVBP Hospital attached to LLRM Medical College Meerut from June 2016 to Sept 2017. Postoperative complications were studied along with the recovery time for all the patients. Statistical analysis was done using IBM SPSS ver. 20 software.

Results: Mean age of study cohort was 36.24±13.81 years with male preponderance (70%). Majority of the patients developed hematuria (n=28) followed by fever (n=3), leakage (n=1), urinary tract infection (n=5) and respiratory complications (n=2). Maximum patients returned to normal activity within 1-2 days after PCNL.

Conclusion: PCNL has become a preferred treatment modality because of minimally invasive procedure and lower rate of complications.