Children with very severe asthma tend to have worse Quality of Life (QOL) than children with milder disease. However recent research has shown that QOL does not correlate closely with asthma control and is a very distinct component of overall asthma health status. Hence from the present literature the current study was planned to compare changes in QOL score with objective measures of pulmonary function and subjective assessment of clinical status, in children with persistent bronchial asthma. The study was planned in Upgraded Department of Paediatrics in the Patna Medical College and Hospital, Patna from Jan 2016 to Dec 2016. The 30 children’s aged 6 -14 years diagnosed with the Asthma were included in the present study. Forced Expiratory Volume in first second (FEV1) and Forced Vital Capacity (FVC) were recorded according to the recommendations of American Thoracic Society. PEFR was measured by Mini Wright’s Peak Flow Meter. Hence from the above data findings it can be concluded that there association of poorly controlled asthma with a poor quality of life. It is recommended that the quality of life of children should be assessed and observed during clinic visits for a better holistic approach and effective improvement of outcome.