Background: Obstetric cholestasis is one of the most common causes of liver disease in pregnancy. Present study was carried out to study feto-maternal outcome in OC in a tertiary care hospital.

Methods: This was a prospective study performed in SMGS hospital from September 2017 to May 2018 in 100 pregnant ladies suffering from pruritus and detected as having Obstetric Cholestasis. They were followed up and maternal as well as fetal-neonatal outcome recorded.

Results: Mean gestational age of onset was 32.25 weeks. Maternal complication in form of sleep disturbance (58%), deranged coagulations profile (15%), PPH (8%) and more number of operative deliveries (65%) were found. Fetal complication were meconium stained liquor (21%), NICU admissions (15%), IUFD (2%), LBW (10%).

Conclusions: Early diagnosis and close monitoring may improve maternal and perinatal outcome.