The current study was designed to assess the effect of physical exercise on resting cardiovascular and cardiovascular autonomic response parameters. 100 healthy volunteers (M68:F32) from age group (17-26) years were included in the study. They practiced some slow walk, calisthenic & stretching exercises daily 1 hour for 3 months. Resting cardiovascular parameters measured were resting HR, SBP, DBP, RPP & DoP. The autonomic function tests to measure the parasympathetic reactivity were deep breathing test (DBT), lying to standing test (LST) and valsalva ratio (VR). For sympathetic reactivity hand grip test (HGT) and cold pressure test (CPT) were performed. All parameters were recorded at start & end of the study. Result showed decreasing trend in all resting cardiovascular parameters (P>0.05). After physical exercise training no significant difference was observed in E: I ratio, 30:15 ratio and valsalva ratio (P>0.05). In Isometric handgrip test (IHG test) rise in diastolic BP in response to the test was significantly decreased from 18.44±6.15 mmHg to 15.66±4.98 mm Hg (P<0.01).The present data provide more evidence to support the beneficial effect of physical exercise training on cardiovascular and autonomic function variables in healthy volunteers.