This is a descriptive survey that determined the Knowledge of Diabetic Foot Ulcer and Foot care Practices among individuals with diabetes receiving care at Tertiary Health Facility in Nigeria. A total of 140 diabetics (91 males and 49 females) were sampled for the study through stratified random sampling technique. Instrument for data collection was investigators’ developed questionnaire which was ascertained for validity. The reliability was determined using split-half method. Values obtained were analyzed using Spearman Brown Rank order Correlation Coefficient which yielded an index of 0.86. Data generated from the study were analyzed using descriptive statistics. Findings revealed that a good number of the diabetic patients receiving treatment at NAUTH, (71.4% males and 73.5% females) have knowledge of DFU and the cause. Majority of the patients know the combination of Oral drugs, insulin and nutrition as treatment modality. Minimal number are aware that daily inspection of feet, trimming of toes, foot bath, exercise practices, use of shoe inserts and wearing of stockings form part of the treatment modality. Greater number of the patients manages their blood glucose level with combination of insulin, oral hypoglycemic agents and nutrition which 44% males and 40.8% females perceive as more adequate than other measures.