Trigeminal neuralgia (TN) is an exemplary condition of neuropathic facial pain. It's often described as a sharp shooting pain or like having an electric shock in the jaw, teeth or gums. It usually occurs in short, unpredictable attacks that can last from a few seconds to about two minutes. The attacks stop as suddenly as they start. In most cases trigeminal neuralgia affects part or all of one side of the face, with the pain usually felt in the lower part of the face. Very occasionally it can affect both sides of the face, although not usually at the same time. In Ayurvedic perspective this condition can be co-related with Anantha vata which has been described under the heading of shiro rogas. A case study of a male patient, 40 years old diagnosed with trigeminal neuralgia since 14 years was treated at National Ayurveda Research Institute for Panchakarma, Cheruthuruthy is discussed in this paper. A course of 49 days treatment was given to the patient at our institute. The treatment protocol comprised of snehana, Swedana, virechana, Abhyanga, Vasthi, karnapoorana, and Shirovasthi. After 49 days course of treatment, patient got remarkable relief in the severity and episodes of the attacks of the head ache.