Comparative administration of ketamine-dexmedetomidine & Ketamine: Propofol for sedation during upper gastrointestinal endoscopy in children
Dr. Bhagwan Das, Uma Shankar Kumar, Dr. Arvind Kumar Aditya, Dr. DK Mishra
In children, dexmedetomidine is currently used in many studies in intra-operative sedation, post-operative analgesia, prevention delirium, and shivering with different dose regimens. In various invasive procedures of children, ketamine and propofol have been popular anaesthetic agents to use, either alone or in combination. Hence present study was planned with the aim to evaluate Ketamine-Dexmedetomidine versus Ketamine-Propofol for Sedation in Children during Upper Gastrointestinal Endoscopy. The patients were divided in two groups as Group A& Group B. The group A having 15 cases were administered ketamine-dexmedetomidine and group B patients having 15 cases were administered ketamine-propofol. All patients administered ketamine 1 mg/kg intravenous. Patients in group A received dexmedetomidine 1 µg/kg bolus dose slowly IV over 10 min and patients in Group B received propofol 1 mg/kg as initial doses. From the above study results it can be concluded that combination of ketamine dexmedetomidine for sedation in children undergoing upper gastrointestinal endoscopy is an effective, reliable and safe alternative to ketamine-propofol without any major side effects.
Dr. Bhagwan Das, Uma Shankar Kumar, Dr. Arvind Kumar Aditya, Dr. DK Mishra. Comparative administration of ketamine-dexmedetomidine & Ketamine: Propofol for sedation during upper gastrointestinal endoscopy in children. International Journal of Medical and Health Research, Volume 4, Issue 5, 2018, Pages 126-128