Background: Leiomyoma of uterus forms the most common type of benign tumor of uterus and also the most common pelvic tumor in women of reproductive age group accounting for 5-20%. They are dependent upon the steroid hormones for their growth and maintenance. Fibroids are usually asymptomatic, however depending on their size, location and hormonal effects, the commonest clinical manifestations are presented as menorrhagia and dysmenorrhoea. The risk of uterine leiomyomata increases as a woman’s age at menarche decreases Objective: To analyze the clinico pathological spectrum in cases of leiomyoma of the uterus Material and Methods: A clinical study of 100 cases of fibroid uterus was conducted in the MDM. Hospital, attached to Dr. S.N. Medical College, Jodhpur from November 2015 to November 2016. The cases are selected by random allocation. On admission, detailed history, clinical examination, and investigations were recorded Results: Leiomyomas are most commonly seen in women of child-bearing age. Majority of the patients (52%) were in 3^rd decades of life. The most common mode of presentation was menstrual disturbances (76 %), among which menorrhagia was seen in 64 % of the cases. Intramural fibroids were the most common variety occurring in 60 % of the cases. Endometrial pattern was proliferative in 96 %. Cystic ovaries were seen in 8 % of the patients. Conclusion: Fibromyoma is the most common benign tumor commonly affects the women of child-bearing age, mostly in the third decade. The most common presentation is menstrual disturbances. Intramural fibroid is the most common variety. The proliferative endometrium was commonly reported.