The study was based on Assessment factors that influence prevalence of HBV, in North Eastern geo-Political Zone, Nigeria. The safety of blood services is one of the major issues has affected with the hepatitis b viruses. Transmission of hepatitis B virus infection through donated blood is reportedly very common particularly in the developing world including Africa, Nigeria and geo-Political Zones. In this context, the objectives of the study were to determine social demography factors that influence prevalence of hepatitis B infections, to examine preventive strategies that eliminate hepatitis B infection, to observe cultural factors that contribute prevalence of hepatitis B infection and to determine the individual factors that influence prevalence of hepatitis B infections. The methods used in this research study were all about questionnaires to collect data structured and unstructured questionnaires were extended to respondents which needed short and precise answers. The researcher used as well, purposive, convenience and simple random sampling methods and sample study determination. Purposive sampling was used to consider the target population, which will be fixed blood voluntary donors and above 18 years of age. Convenience sampling was used to determine the study population that would be readily available. Simple random sampling was used to pick any subject within the sampling frame in order to reduce bias within the study by giving the questionnaire at random to those subjects who would accept aged above 18 years. The study findings established that the youth were highly constituted the majority of our respondents. These may be easily affected due the adolescence stages that are faced which lead them to experience intersex without any protection and misuse medical instruments. Preventing injuries from sharps and needle sticks is considered a part of the "routine practices" used by healthcare worker; therefore, it is relevance and test before any relationship for partners and community vaccination to lessen its propagation. The risk of infection from contaminated needle sticks is much greater than the risk of spreading HIV by this method. In the United States, illegal drug use injection accounts for about 16 percent of new hepatitis B infections. But this was not the case of awareness about this virus propagation by agents working in north eastern zone of Nigeria. The researcher recommends that The government should sensitize the community to under do vaccination against hepatitis B., improving education among girls, especially beyond primary school needs to be strong encouraged by the Government as education has an impact on the women decision on the place of delivery and within house hold to lessen hepatitis B propagation, first-aid should be immediate if there has been exposure to blood or body fluids.. Hence, follow the employer's procedure for further testing. First-aid will include: Thoroughly rinsing the injury site with running water, and gently cleaning with soap and water if possible; eyes, nose, or mouth should be flushed with running water and non-intact skin should be rinsed thoroughly.