The relationship between serum uric acid and dyslipidemia is also complex and not fully elucidated. In recent years, atherosclerotic diseases and Coronary artery disease (CAD) have become important causes of mortality and morbidity in patients with gout. The objective of our study was to investigate the independent relation between serum uric acid and lipid profiles. This study had been conducted in the Department of Biochemistry AIIMS Patna on adult patients who were referred from Out-Patient Departments (OPD). Relevant demographic, personal, medical and surgical details of the patients are recorded in the department during their enrolment for biochemical investigation. All the blood samples were analysed on fully automated clinical chemistry analyzer, Beckman Coulter AU 480. Total 633 blood samples reports records were analyzed retrospectively from records for this study. Our study showed significant higher levels of uric acid in dyslipidaemic subjects. Since dyslipidaemia predicts the risk of CAD, it is important to consider uric acid levels in these patients for more comprehensive strategic management of risk factors and Visa-versa, while establishing the diagnosis of hyperuricemia, clinical suspicion of coexistent dyslipidaemia should also be considered.