Lipoproteins play an important role in the transport of plasma lipids; their increase or alteration in various fractions may be responsible for hypercholesterolemia, in nephrotic syndrome. The present study is designed to study the derangement of serum lipids in nephrotic syndrome and to know whether any correlation exists between serum lipids and albumin The study has planned in Nalanda Medical College and Hospital. This is a Cross sectional study in which 25 Normal patients and 25 patients with nephrotic syndrome aged 15 years and below. The Group A includes 25 Normal patients and Group B patients includes 25 Nephrotic syndrome patients. From the present study it can be concluded that in nephrotic syndrome, there is generalized hyperlipidemia and hypoalbuminemia. Although hyperlipidemia is most marked when serum albumin is low, yet no definite correlation can be established between the degree of hypoalbuminemia and rise of lipids. Hyperlipidemia of the nephrotic syndrome may be related to the progression of glomerulosclerosis through an increasingly vast array of lipid mediators affecting inflammation, glomerular blood flow and fibrosis.