Introduction: Asana, pranayama, and meditation are three main techniques of yoga. Studies on long-term yogic practices have shown improvement in cardiovascular functions. Aim: The aim was to study the short-term effects of pranayama and meditation on cardiovascular functions in asthmatics. Material and Methods: It was a prospective interventional study done in a tertiary care centre in North India. It included 120 non-smoking patients, in the age group of 18-50 years, diagnosed with mild to moderate grades of asthma. They were randomized in two groups i.e. Group A (Yoga training group) and Group B (Control group). Yoga training group underwent 90 minutes daily yoga program for 4 weeks. Pre and post yoga cardiovascular functions were assessed by recording pulse rate, systolic blood pressure, diastolic blood pressure and mean blood pressure. The parameters were statistically analysed using SPSS 16 and p-value<0.005 was taken as normal. Results: There was significant reduction in resting pulse rate, systolic blood pressure, diastolic blood pressure, and mean arterial blood pressure after practicing pranayama and meditation for 4 weeks Conclusion: This study showed beneficial short term effects of regular pranayama and meditation practice on cardiovascular functions in asthmatics.