Preterm birth is a major global health issue, with 15 million preterm births occurring each year, and over 1 million of them dying each year. Preterm birth complications directly account for greater than 35% of all neonatal deaths each year because it increases the risk that an infant will die from infection. Preterm births are on the increase globally, both in high and low-income countries. A significant proportion of death among preterm and low birth weight infants is preventable. Kangaroo mother care is a method of care of preterm and low birth weight infants and involves the infants being carried usually by mother with skin to skin contact. This study was conducted to determine the awareness, practice and effectiveness of Kangaroo Mother Care amongst postnatal mothers in Aminu Kano Teaching Hospital Kano, Nigeria. A descriptive cross sectional design was adopted for the study. A structured questionnaire with close ended questions was used to collect the data. The data was analyzed using the Statistical Package for Social Sciences (SPSS) version 22 and presented in frequency distribution tables and percentage using. The findings revealed that 61% of the respondents knew about Kangaroo Mother Care and 57% practiced it. All the respondents who practiced it believed that it has a positive effect on the physical well-being of the infants with a significant weight gain during the period of care. It was recommended that a wider public health campaign be carried out to sensitive the public on the importance of the care.