Iron is one of the most important micronutrients for good health and disturbed iron metabolism leads to lipid-protein oxidation and also damages RBC membrane. Various research studies found that the reactive free iron or iron overloads was responsible for diabetes. The exact mechanism by which the altered iron metabolism leads to disease like diabetes is remains not understood. Hence the present study was planned to evaluate the iron profile in type 2 diabetes mellitus patients. The present study was planned in the Department Of Biochemistry, Jawaharlal Nehru Medical College, Bhagalpur, and Bihar. Total 50 patients were enrolled in the present study. The 25 patients were enrolled in the group A as control cases and remaining 25 cases of diabetes were enrolled in group B. All the patients were undergone the biochemical evaluation as per standard protocol. The findings of this study is in accordance to earlier studies, that there is dyslipidaemia, increased lipid peroxidation, inflammation and oxidative stress in diabetics compared to non-diabetics; and the oxidative stress further increases as diabetes to cardiovascular diseases. The evaluation of iron profile can be a useful outcome of the predictable studies on diabetes and related complications. Elevated iron and ferritin is a risk factor for diabetes and produce many complications. Proper management must be taken to remove the excess iron that can be very harmful to the body.