Background and Purpose: We tried to explain the manner by which organized inpatient (within stroke unit) care can deliver decreases in case fatality and in the requirement for institutional care after stroke. Methods: We tried to perform an analysis of a cooperative systematic review randomized trials that compared inpatient in stroke unit care with alternative forms of care. Twenty-eight trials (5855 patients) provided outcome information on death, spot of living location, and last functional outcome. also an analysis of a variety of subgroups examined the impact of stroke unit on patient death, institutional care or dependency. When dealing with missing data for the outcomes of death, dependency or institutionalization, we assumed the participant to be alive, independent and living at home. We aimed to explore the implications of these assumptions in sensitivity analyses. Results: The decreases in case fatality of patients treated in a stroke unit setting were more progressed after the index stroke. The decreases in the chances of death were apparent in particular for those deaths considered to be secondary to immobility. The relative increment in the number of patients sent home from stroke units compared to alternative general medical care was owing to an increase in the number of patients returning home physically independent. Over the scope of stroke severity, stroke unit care was related with non-significant increments in the increases in the number of patients regaining independence. Conclusions: Inside the constraints of the accessible data, we conclude that organized inpatient stroke unit care most likely benefits a wide scope of stroke patients in many different ways, i.e., reducing death from secondary complications of stroke and reducing the urge for institutional care via reduction in disability.