Loss of vertical dimension of occlusion can occurs when enough teeth are lost that the remaining teeth and supporting alveolar bone are unable to withstand even normal biting forces, and begin to tip sideways. The Causes of multiple tooth loss are many, resulting in over-closure of the jaws which requires complex rehabilitation to correct. This clinical case report describes the management of a 50-years-old female patient with a worn out anterior upper teeth opposing mildly attrited anterior lower teeth with a loss of maxillary and mandibular posterior teeth. The case was treated by restoring the lost of vertical dimension by prosthetic rehabilitation.