Endoscopy done to evaluate the mucosa in patients with symptoms of GERD usually reveals erosions or ulcerations at the squamocolumnar junction, or Barrett’s oesophagus which is diagnostic of GERD. Endoscopy is the most sensitive diagnostic test for peptic ulcers. The main role of endoscopy in patients with uncomplicated Peptic Ulcer disease is to confirm the diagnosis, identify lesions too small to be detected by radiographic examination and to rule out malignancy by performing endoscopic biopsy. Hence based on above literature findings the present study was planned to Clinical Assessment of the Patients Suffered from Gastro Esophageal Reflux Disease (GERD) Diagnosed with Endoscopy from Bihar. The present study was planned in Department of Gastroenterology, Ruban Memorial Hospital, Patna, Bihar, India. In the present study 50 patients diagnosed of Gastro-esophageal reflux disease (GERD) based on upper gastrointestinal endoscopy (UGI scopey) were enrolled. Patients who had been diagnosed as gastro-esophageal reflux disease (GERD) based on upper gastrointestinal endoscopy were included in this study. UGI scopy had been considered the gold standard diagnostic test for the diagnosis of gastro-esophageal reflux disease. The data generated from the present study concludes that higher age of the patient infers higher risk of complications. Daily episodes of heartburn, regurgitation and retrosternal chest pain implies higher risk of complications. Some other studies also showed similar results with higher complications seen in increasing age and increased frequency of symptoms.