Stem cell therapy is the new technology used to collect stem cell from bone marrow, peripheral blood and umbilical cord of newborn and introduced into human body for treating various disorders. The newborn disorders like broncho-pulmonary dysplasia, intra ventricular hemorrhage, hypoxic ischemic encephalopathy can treat by stem cell therapy. For infant lymphoblastic leukemia, cerebral palsy, metabolic disorders like krabbe disorder, sanfillipoo syndrome can be treat with stem cell therapy. Childhood disorders like blood disorders, metabolic disorders, immune disorders, cancer (leukaemia, lymphoma, myeloma), myelodysplastic syndrome cure by stem cell therapy. Neurological disorders like Parkinson’s disease, alzhemier`s disease, spinal cord injury, stroke, cerebral palsy, batterns disease, amyotrophic, lateral sclerosis are treated by stem cell therapy. Heart diseases, burns, diabetes also treat by stem cell therapy. Stem cell therapy used for anti aging therapy. Nowadays, it shows great promise for regenerative medicine.