World Health Organization has defined ‘adolescence’ as a period between 10-19 years. In Indian context, adolescents constitute over 21.4% of the total population and this age group needs special attention because this period is very crucial since these are the formative years in the life of an individual when major physical, psychological and behavioural changes take place and additional roles and responsibilities are expected from them. In many societies puberty onset is celebration time, it announces acquisition of fertility. However physiological social, cultural forces make it stressful, difficult transition for many. In India very little attention is paid to reproductive health of adolescent girls comprising 22% females. Reasons for neglect are ignorance, indifference, reluctance of parents & girls to consult a Doctor. Hence the present study was planned to evaluate the endocrine abnormalities in adolescents with menstrual disorders. The present study was planned in Department of obstetrics and Gynaecology, Darbhanga medical college and hospital (DMCH), Darbhanga, Bihar, India. The study was conducted from November 2017 to June 2018. Total 50 school going Adolescent girls aged from age 10 years to 19 years were enrolled in the present study. These were divided in the two study groups as Group I and Group II. Group I consists of case and Group II consists of control girls. The available literature indicates, majority of these student population experiences menstrual related symptoms and disorders of various degrees. These symptoms can have unbearable effects on student quality of life and daily activities. However, race, ethnicity and culture may influence expression of menstrual symptoms and their severity. The data generated from the present study concludes that majority of adolescents with menstrual disorders in their study had menorrhagia, short cycles or prolonged menstruation. Less frequently they had secondary amenorrhea, dysmenorrhea, oligomenorrhea, and primary amenorrhea. They suggested that long-term follow up and management is necessary for adolescents with menstrual disorders.