Dengue has recently become a major public health problem causing significant morbidity, mortality and economic loss. Dengue is endemic in more than 100 countries. Worldwide around 2.5 billion people live in dengue prone regions and about 100 million new cases are detected each year. The WHO 2009 classification divides dengue fever into two groups: uncomplicated and severe; though the 1997 WHO classification is still widely used, classifying dengue in to 3 groups: dengue fever (DF), dengue haemorrhagic fever (DHF) and dengue shock syndrome (DSS). Hence present study was planned to evaluation of dengue fever with in childrens admitted to ANMMCH with clinical & laboratory evaluation. The study was conducted in Department of Paediatrics, ANMMCH, Gaya, Bihar from Jan 2018 to Sept 2018. Total 50 cases of the childrens diagnosed with dengue were enrolled in the present study. Detailed history and careful clinical examination was performed on each patient. Laboratory investigations done were hemoglobin, total and differential leucocyte counts, platelet count, haematocrit, liver function tests, blood urea and serum creatinine, chest radiograph and ultrasound scan of abdomen. Blood counts were monitored periodically as and when required till resolution. Other differential diagnosis was excluded by appropriate tests. The patients were classified according to revised WHO guideline and managed appropriately. Fever, myalgia and headache were most common symptom and hepatomegaly was most common finding in cases. Dengue is an important cause of mortality and morbidity. It presents with varied clinical manifestations. In view of the increasing burden of dengue on the public health-care system one should have a high index of suspicion. Early diagnosis and prompt intervention may help in reducing the mortality and morbidity.