Objective: To evaluate maternal and fetal outcome in cesarean section using spinal or general anesthesia. Study design and setting: Observational descriptive study at AL -Elwiya Maternity Teaching Hospital from the beginning of October 2013 to the beginning of October 2014. Materials and Methods: Pregnant ladies undergoing cesarean section (C/S) were enrolled in this study. Sample collection was on Sunday and Wednesday each week throughout this period, the selection of cases was done after decision of C/S. Full history, examination, investigations, indications of c/s, type of anesthesia, intra and post-operative events for both mother and fetus were recorded and all patients were followed for one week after doing the operation, total number of patients was 110 cases of these sixty patients received spinal anesthesia (SA) and fifty received general anesthesia (GA). Informations obtained on admission plotted on special informations form. Results: Chest infections and preeclampsia were significantly (P<0.05), the more frequent medical diseases, in SA group. In the current study blood loss in SA group was significantly less than that in GA group (<0001). It had been significantly found that women of SA group started bowel motion earlier than those in GA group (P<0.001), women in SA group needed shorter hospital stay (P<0.05). Regarding wound infection it was significantly more frequent in SA group than GA group (P<0.05), study reported difficult intubation and aspiration pneumonia in one woman represented 2% of GA group. In SA group 25/60 women developed post spinal headache (41.66%). Neonates of SA group had higher Apgar score at 1 min (P=0.036), and at 5 min (P=0.028) than those with GA, and less likely to be admitted to neonatal care unit (P=0.022). Conclusion: Spinal anesthesia is a safe type of anesthesia in C/S, as pregnant ladies received spinal anesthesia during C/S they had less intraoperative blood loss, better neonatal outcome and the complications were not highly morbid as complications of general anesthesia.