A total 100 samples of patients with chronic suppurative otitis media (C.S.O.M.) were studied bacteriologically. Ear infection was found to be more common in paediatric population (70.96%). Males suffered more than females. A total of 124 bacterial isolates were seen with preponderance of gram negative bacilli. Pseudomonas (38.7%) out-numbered others. Ciprofloxacin, Piperacillin, Amikacin and Gentamicin were found to be the most effective drugs.