Introduction: Mental health disorder constitute is a major public health problem which is globally contributed to 13%of the global burden of disease measured as disability adjusted life years. Now a days it is a higher burden in low and middle income socioeconomic countries like Bangladesh. The reported prevalence of mental health disorders varies from adult 6.5% to 31% and children13.4% to 22.9%.There is a negative attitude towards the treatment of those affected children. The treatment is not a priority in health care delivery. But it is important to increase mental health care delivery system in tertiary care hospital in big cities as well as in primary health care. Objective: To find out the socio-demographic characteristics, incidence and burden of mental health issues in Dhaka Shishu (Children) Hospital. Methodology: This retrospective study was carried out from mental health clinic in Dhaka Shishu (Children) Hospital since January 2017 to December 2017. Result: Result showed that 196 children with mental health issues were seen in mental health clinic at Dhaka Shishu (Children) Hospital, among them the incidence of mental health problem 5.2% of those ASD was (57%) Intellectual impairment with speech delay (10.58%) ADHD (7.21%) behavior problem (4.40%) ASD with ADHD (2.88%) learning difficulty (2.88%) others (10.9%). Male are predominant (3.16:5). The age group of the most children were >2 to 5 years (48.1%) and 5 to 9 years (37.5%). The children came mostly from higher wealth quintile (52%). Among male average total difficulty score was 16.55 ± 2.8, and among female average total difficulty score was 17.22 ± 3.5, No sex difference in total difficulty score or individual scale score was found following independent t test (P>.05). Conclusion: The burden of mental health disorder is increasing in Bangladesh day by day, so far the children with mental health disorder unrecognized and under-researched area. To improve the mental health services in Bangladesh for early intervention, epidemiological survey and clinical research are needed. Also need to increase well trained multidisciplinary professionals to provide proper services to the tertiary and primary health care center.