Ultrasonography is an easy to perform, non-invasive, inexpensive and safe imaging technique that is invaluable in India, where AIDS is prevalent and where sophisticated diagnostic tools are not readily available. The present study was planned with the fact that there is relative lack of literature and studies regarding USG findings in HIV infected patients in Indian subcontinent. The present study was planned in the Department of Radiology, Government Medical College, Betiah, Bihar. From Feb 2018 to April 2019.Total 50 HIV-positive patients were enrolled in the present study. The ultrasound scans were performed after an overnight fast of at least 12 hours with patients lying supine and using a 3.5–5.0 MHz frequency curvilinear probe on an ALOKA 1700-SSD ultrasound machine. Non-fasting patients, children, and patients with incomplete ultrasound examinations were excluded from the study. Two radiologists performed all sonographic examinations. Abdominal ultrasonography is an excellent and sensitive modality for routine screening of HIV infected patients. The provision and availability of sufficient clinico-pathologic data in the future would improve the quality of ultrasonographic diagnosis and treatment in these patients. Physicians should exploit this widely available and relatively affordable technology in the management of HIV/AIDS patients with abdominal symptoms.