Intravenous drug use is associated with many medical complications. Some infections like Hepatitis C, Hepatitis B and HIV are particularly troublesome. The current study was planned to find out the prevalence of Hepatitis C in intravenous drug users. In addition, the knowledge of such patients regarding HCV infection and barrier to treatment perceived by such patients for getting treated were studied. A total of 268 patients were evaluated for their HCV status. 42.16 % patients had current HCV infection. The prevalence of HCV was more in adolescents, singles, those from lower socio-economic classes and those with poor social support. Knowledge regarding HCV infection in IDUs was very poor. About 17% did not seek treatment for HCV infection despite being told to do so. Financial constraints were the main reasons for not seeking the treatment.