Comparison of two different doses of Dexmedetomidine added to Bupivacaine in patients posted for upper limb surgery under supraclavicular brachial plexus block
Anjna Badhan, Sonali Kaushal, Vikas Panwar
Objective: To compare the effect of two different doses of dexmedetomidine toBupivacaine, on onset and duration of analgesia for supraclavicular brachial plexus block in patients scheduled for upper limb orthopedic surgery. Methodology: Present study was a prospective randomized double blind comparative study,conducted on 60 patients aged between 18-60 years after ethical committee approval and informed consent, which were scheduled for upper limb surgery and randomly divided into two groups, 30 patients in each. Group D1 received LA (0.5% Bupivacaine 12.5ml plus Lignocaine Adrenaline 12.5ml plus dexmedetomidine 1 µg/kg diluted with normal saline up to 5 ml total volume 30 ml) and Group D2 received LA (12.5ml of 0.5% Bupivacaine plus Lignocaine Adrenaline 12.5ml plus dexmedetomidine 2 µg/kg diluted with normal saline up to 5 ml total volume 30 ml). The onset and duration of sensory and motor block, duration of analgesia, hemodynamic parameters, sedation score, VAS and side effects were recorded in two groups. Results: Onset time of sensory and motor block were earlier and duration of analgesia were longer in Group D2 than in GroupD 1 (p<0.001). There was no significant difference in the incidence of hypotension and bradycardia between both the groups (p > 0.05) and also found reduction in number of rescue analgesic doses consumption in 24 hours in GroupD2 than in GroupD1.
Anjna Badhan, Sonali Kaushal, Vikas Panwar. Comparison of two different doses of Dexmedetomidine added to Bupivacaine in patients posted for upper limb surgery under supraclavicular brachial plexus block. International Journal of Medical and Health Research, Volume 5, Issue 8, 2019, Pages 124-127