International Journal of Medical and Health Research

International Journal of Medical and Health Research


International Journal of Medical and Health Research
International Journal of Medical and Health Research
Vol. 5, Issue 8 (2019)

Chronic kidney disease and its associated risk factors: A case control study


Omeire CA, Oparaocha ET, Abanobi OC, Ibe SNO, Nwoke EA

Chronic kidney disease (CKD) has become a global health issue and with the rising cost of nephrology care, there is need to understand the risk factors which predispose to its development and the consequent means of mitigating its development and progression. This study on “chronic kidney disease and its associated risk factors: a case-control study” was carried out on adults within the area under study to ascertain the association between CKD and some risk factors of interest to the researcher. This study involved 109 cases who were matched by age and sex with 109 controls, all drawn from the same population. The results show that hypertension (p = 0.030; 95%CI =0.321, 0.944), obesity (p = 0.014; 95%CI =1.175, 4.303), alcohol use (p = 0.021, 95%CI = 0.055, 0.790), and awareness of the disease were found to have statistically significant association with CKD whereas diabetes (p=0.6695, 95% CI= 0.373, 1.929), smoking (p = 0.596; 95%CI =0.325, 7.069), age, and sex did not show statistically significant association with CKD in this study. Having a relationship with a person diagnosed of CKD was the only variable that had a statistically significant association with respect to family history (p = 0.011, χ2 = 9.00). However, the odd for CKD was lower in the non-diabetic subjects by 15% (16% in the adjusted analysis). The same was observed with sex where the odd for CKD was found to be about 1.3 times (OR=1.282) higher in females than in males. For the fact that the risk factors of CKD have been found to vary between countries and climes, it is expedient that they be studied in smaller geographic locations in order to detect the risk factors a particular area is prone to. This therefore underscores the need for increased emphasis on screening and managing the modifiable risk factors early enough so as to forestall the development and progression of the disease, seeing that the course of the disease is irreversible in nature.
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How to cite this article:
Omeire CA, Oparaocha ET, Abanobi OC, Ibe SNO, Nwoke EA. Chronic kidney disease and its associated risk factors: A case control study. International Journal of Medical and Health Research, Volume 5, Issue 8, 2019, Pages 158-162
International Journal of Medical and Health Research