International Journal of Medical and Health Research

International Journal of Medical and Health Research


International Journal of Medical and Health Research
International Journal of Medical and Health Research
Vol. 5, Issue 8 (2019)

Clinical evaluation of levels of antithyroid peroxidase antibodies in women with polycystic ovary syndrome from Bihar


Dr. Sunita Kumari, Dr. Vijaya

Thyroid disorders and polycystic ovary syndrome (PCOS) are two of the most common endocrine disorders in the general population. Although the etiopathogenesis of hypothyroidism and PCOS is completely different, these two entities have many features in common. An increase in ovarian volume and cystic changes in ovaries have been reported in primary hypothyroidism. In the other direction, it is increasingly realized that thyroid disorders are more common in women with PCOS as compared to the normal population. Hence the present study was planned to evaluate the levels of antithyroid peroxidase antibodies in women with polycystic ovary syndrome. The present study was planned in Department of Obstetrics and Gynaecology, Patna medical college and Hospital, Patna Bihar and JLMNMCH Bhagalpur Between October 2018 till july2019. Total 30 females were enrolled in the present study. Out of the 30 females, 15 females were evaluated in the group I as study group patients with polycystic ovarian diseases. Remaining 15 cases were evaluated in the control group cases. These control group females are with reproductive age with regular menstrual cycles, no signs of hyperandrogenism, normal ovaries on pelvic ultrasound examination and normal level of free testosterone. The various parameters like TSH, free T4, antithyroid peroxidase antibody, total testosterone were measured in the all patients. The type of assay used was chemiluminescent immunoassay (CLIA). PCOS and Hypothyroidism are closely related. There is increased prevalence of hypothyroidism in PCOS. The symptoms of both PCOS and hypothyroidism are similar. PCOS patients with hypothyroidism have increased prevalence of menstrual complaints like oligomenorrhoea and secondary amenorrhoea. The pathophysiological pathway and contributing factors behind this association are yet to be elucidated. Long-term studies are required to assess the significance of thyroid dysfunction in patients with PCOS, especially on fertility.
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How to cite this article:
Dr. Sunita Kumari, Dr. Vijaya. Clinical evaluation of levels of antithyroid peroxidase antibodies in women with polycystic ovary syndrome from Bihar. International Journal of Medical and Health Research, Volume 5, Issue 8, 2019, Pages 211-215
International Journal of Medical and Health Research