Aims and Objectives: To establish the role of USG and CT in diagnosis of gallbladder malignancies. To see sensitivity and specificity of the USG and CT findings.

Materials and Methods: This was an observational study that was carried out on thirty patients with Gall Bladder Malignancy over a period of eighteen months. Ultrasonography of abdomen with subsequent CECT abdomen was then performed in same cases. The patients who presented with complaints of pain, jaundice, itching, weight loss and upper abdominal mass were assessed. For CECT abdomen, patients fasted for at least 6-8 hours before the examination. The findings were then correlated with Histopathology report.

Results: Out of 30 patients, 6 (20%) were males and 24 (80%) were females. The mean age of the study subjects was 56.17±11.01 years. Maximum subjects were in the age groups of 51-60 years (40%) followed by >60 years (23.33%). The sensitivity of USG in differentiating GB carcinoma from inflammatory lesion was 23/25 (100 = 92%), while the specificity of the test in correctly differentiating those who did not have the disease was 3/5 (100 = 60%). The positive and negative predictive values of the test were 92% and 60% respectively. The diagnostic accuracy of USG was 86.67%. The sensitivity of CT in differentiating GB carcinoma from inflammatory lesion was 26/27 (100 = 96.69%), while the specificity of the test in correctly differentiating those who did not have the disease was 3/4 (100 = 75%).

Summary and Conclusion: As the histopathological diagnosis of the present study correlated well with USG and CT scan findings in the diagnosis of gallbladder carcinoma; it can be concluded that both USG and CT scan are useful imaging modalities for diagnosing this disease. However, CT scan has some is more sensitive and specific in predicting gall bladder carcinoma as compared to USG.