To evaluate the prevalence of different types of cancers in South Indian Hospitals among defined population. Cancer is uncontrolled growth of abnormal cells in the body triggered when body’s normal control mechanism stops working. Almost 75- 80% of patients have advanced stage of disease at the time of diagnosis. The study data was captured from Regional Hospitals among South Indian Population for a duration of 6 months. The results were evaluated from a statistical database. Breast Cancer is the major cause of morbidity and mortality when compared to other types of Cancer. Age groups of 50 – 58 years where at higher risk of Cancer. In constarst, age groups of 30-39 years and ≥ 60 years were at equal risk of Cancer.