Exogenous and endogenous risk factors govern the risk of progression from exposure to the tuberculosis bacilli to the development of active disease. An exogenous factor makes the progression from exposure to infection more prominent among which the key factors are the bacillary load in the sputum and the proximity of an individual to an infectious TB case. And progression from infection to active TB disease is lead by endogenous factors. Emerging factors such as diabetes, indoor air pollution, alcohol, Immunosuppressive drugs, tobacco smoke also play a significant role along with well-established risk factors. Hence based on above reported findings the present study was planned for Study of Level of Vitamins and HbA1C Status in Patients Suffered from Tuberculosis Along with Diabetes from Bihar Region. The present study was planned in Department of General Medicine, Nalanda Medical College and Hospital Patna, Bihar, India. The 20 cases of the diabetes diagnosed with the tuberculosis were evaluated as cases and 20 cases of the normal cases were evaluated as a control cases. The data generated from the present study concludes that the levels of the HbA1C were increases in Diabetes patients with TB whereas the levels of the Vitamin D and Vitamin B12 were decreases in diabetic patients with TB.